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InVitria Blog | Cell Culture and Biotech Manufacturing Insights

Recombinant Albumin for Stabilization of Live-Attenuated Viral Vaccines

Posted By Jeanne McAdara Ph.D. on 4/16/19 2:00 PM

Enhanced liquid-phase stability of live-attenuated Flavivirus vaccines using recombinant albumin

The single-stranded RNA viruses belonging to the genus Flavivirus (family, Flaviviridae) are significant to global public health due to the high rates of morbidity and mortality they cause.1 For example, Yellow Fever sickens approximately 200,000 people and kills 30,000 annually.2 Other viruses belonging to this genus include the mosquito-borne diseases Dengue Fever, Japanese encephalitis, West Nile virus, and Zika virus, and the tick-borne diseases Tick-borne Encephalitis, Kyasanur Forest Disease, Alkhurma disease, and Omsk hemorrhagic fever.

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