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Transferrin: An Iron Transport Protein - Recombinant Human Transferrin in Cell Culture Media

Posted By Randy Alfano on 5/16/18 11:17 AM

Transferrin is an iron binding protein found in blood plasma that is critical to cell health. Transferrin supplies iron to cells naturally in the body and as a supplement in cell culture media.

Transferrin Function and Structure

Human serum transferrin, a bilobal ~75 kD glycoprotein that has the ability to reversibly bind Fe3+ with nanomolar affinity, represents one of the major vehicles for iron delivery to cells both in vivo and in vitro3. Produced in the liver, transferrin is found in the blood plasma as a heterogeneous population at approximately 2.5 mg/mL consisting of diferric (holo or iron-saturated), monoferric N-lobe, monoferric C-lobe (partially iron saturated) or apo transferrin4.

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InVitria's Top Insights from ISCT 2018 - Montreal

Posted By Attie Pennybaker on 5/15/18 4:00 PM

The International Society of Cell & Gene Therapy (ISCT) has a rich history of bringing together leading professionals who are committed to advancing the field. This year, from May 2nd to May 5th, nearly 1500 of those leading professionals from across the globe gathered in the bustling Canadian city of Montreal to share the latest breakthroughs and innovations, partake in thought-provoking conversations, and create lasting connections at the ISCT 2018 annual conference. Although I did not get a chance to indulge in the famed Canadian poutine dish, I left the country full of something better: new ideas, deeper knowledge, and a greater appreciation for the potential implications and benefits of cell and gene therapy innovation.

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3 Takeaways from the World Vaccine Congress 2018

Posted By Attie Pennybaker on 4/11/18 10:16 AM

Innovation, technology, and success has driven the vaccine industry to remain at the forefront of biotechnology and this year’s World Vaccine Congress was no exception. Taking place April 2-5 in Washington D.C., the 18th annual World Vaccine Congress lured over 1000 attendees from more than 300 leading global institutions to deliver the largest establishment of this event yet. Being surrounded by such a vast amount of knowledge and key influencers, my experience representing InVitria here was one full of inspiration.

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